SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8f4be74e313906bdb70d8c1b23a7d6ecdc2069ecd98e593603847b443bce2b' 
  AND token = 'A27HGDPV/pgedVAr8soIhdLrV/pD9GIipAICM1PauWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}