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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0900b0e29ea91946d1c8afbbf6e798621d89d053a2707de0f3f5fe6b5adec7' 
  AND token = 'TlX3hKHk+65Et9rx4a6Jhg4fRDVOATNd0Pp8ZFY9t58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}