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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2d3ee882b2ad9257641e2c636f4d6627f5643c06ea46daf9fd02fa128f35a6' 
  AND token = '4/bxHMncSUSTLkjsCRBanB01UZ5PsnqFvGuAt1/nfks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}