SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcf9163afe2e69ea0cca165fb8c6a8a48b314f819552cd17c1d08ec05fabb59e' 
  AND token = 'gG7eMG8yWqEcc2UAkSEpD2jt8tuRsBh9cUiwEPiAfes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}