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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f7dd394caa788fd0ed3a1e894660ce35a50babb87ab47b2600275822dcb35d3' 
  AND token = 't0/jf1md344704DWY+91u+kZ8yixHVHVW9PZA/BS7Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}