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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8327c5672f6789756f081cd9639733039aeea7aaafcadfc911e8a4cb0735015' 
  AND token = 'Zkn31cKs+zpuUfN8EBqRxsTU8AHIw2h2dIhQ0MXclQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}