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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bf94760c20f11fb04c9451bd437727f8f834b2c897c577d77c92bae6313fe0' 
  AND token = '+RFoc28v+T+erF/Uvym4E1q9z4kfhhWferbOwl7RMiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}