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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7597b72f9b99a7f4f2a5a47033713b0fd6cce5da92668ebf6b0a612391702f99' 
  AND token = 'KW/euQD1HDEQrAFPpuPSTFfVI++nT6qmqNG0RUt88uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}