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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11ff87945dcd477624f2a9b482cbb7aa91ba93757bf2f25e9457327c4b8c4190' 
  AND token = 'C8YtJ8z7dP0sFD89m8saEUCH3XaQh4fFJyaO/EfJLww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}