SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57c140ebdc36d649b4c4e5410c18d87e39b784241d4a598f76db67196614dc4' 
  AND token = '6PQE2IJp6emblxMss/q4hXmmlGYjFYjUUQLmkwyfa9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}