SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a2b8d7c66616b7dc0b9a5a66d421c1586340248f55cc02889469e095fc0ae0' 
  AND token = 'uYQL6neT8GByJdm8UjrrIRyxCORUz59O5J9rvEyvBpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}