SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca351b7a19b18fbffa72692748abed27994d4012c6581abb9811be00e81eaec' 
  AND token = 'LPdCBMSoAeaehh+SDVrhwzjth/IEvEcszrWrHQm2EeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}