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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5722debcd53a720cf792cf5ae047f93ee5d6deaa493e7d96dfa494a28f1194' 
  AND token = 'fUKUEh1E5RAdxH1nBGD1s5yGquHD6l0hlsWyHvt5qsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}