SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceef38daae4001a9597d9973a420a4558cadb1701c0e129763a68a450fb27e48' 
  AND token = 'roaqOFiRr0I364pUftAZc2iKz43XBu0YO12G1SeC8DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}