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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e1b4d648c2c2bccd7298d0a543221c7c4424aa9811ad76fb9e47d59106f578' 
  AND token = 'lVfCH6mGxj0nH5QfFn/KoieCMf5YXh5jxAks043pdtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}