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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a268ac47df05102a3a1560a9b4d6340f8341950c8cf8bac12a89207bdc1b88e' 
  AND token = '8UFkusZkWyBpX+lA6bIzkHMgqvCvBv/BuWu5dKG0ArA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}