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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fcb77e83aa6edd1e4c27c6b81367a51a844761312dee7652daeb7cfee0d8621' 
  AND token = 'U00oksXO1fF1BTv6N7lx/TMBz+hZIOIAN0NozPMYwvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}