SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8601efe6b9959c6cce894c403b4f9a04f3eb13f3371f8d90c9493a4119b094' 
  AND token = 'Lbz/p/UT10Pi7K81pREHJeqdVfS7Tt8NYbbl6Dh5KjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}