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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7202e58fd3086b83470394c24c02887f349da1f443f6bfb018406f43c81400ce' 
  AND token = 'cFt4wwDuls0fkNhbLJjCKAtB+JvWJoQBW9j/vE745yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}