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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293d0d3f7357f1715fd883616e2484ec58b799f21fcf1c78a6389253ff284238' 
  AND token = 'd9VDtW7JFq9kv/rUqQWYM7dN3TJBh3gX4nnT7kxqfNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}