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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15a8d211d828ae9b7f0055a38e27232ad8b946f34151e1c3a6c7c85ed9da490' 
  AND token = 'pROyqQ50F6Pc9uI7oqxVxwXDZSKxvPfSr+SMtzlbZpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}