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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3266e183a5e32b56140eea0cfecda6b5b0e706f53504d6fa532b2c5796ca1cc' 
  AND token = 'VkLo0fVR17SglhGoPwL2AKnMYQuH8ErV4hSuHRuUdOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}