SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be8853242a993d674cd5fed46c36531f32c409ad0ee99c8afd473dda3815680' 
  AND token = '1ilTCqmu+fUZsoHY8M4YKWmfxSw2zbk6snmvyNNzzQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}