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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0613a68ffc34e245d27b9fd1a7d00b125a75000316f3fd35f5c1fe04bf9aefc7' 
  AND token = 'UMyB189d4I98tRtsoDDHz4fNaI7Cu7gn9z0CDhD+ojE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}