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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2485f22859c429845cca1fd01c27ff88b53928ea6294333e3fbe78d9791d3c6' 
  AND token = 'PtBOa4ve8ruPRWjoX+l3qiSceJ46/loiPwkF7HMv+zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}