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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c0092c157d87591178d409613f2e72a5885a6a6ff3e3542e74e00860f46367' 
  AND token = 'A+iJWpNtjdGQzRn1yMybqs4xjl1LJZv6lAGXuWQRl7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}