SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616014231de2f6702c2bc02a82f84a2b650fd4501b1576568af03152d6bdd088' 
  AND token = 'KZUTqXKJfZKUcbi4jGBXXSsNTph4rxPWdixDSFIN/Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}