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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ad19b5596e79f58f0b49a81991b90af9f58b3147bdad7282da23dce35d37e1' 
  AND token = 'g4r9CEVg5Md994Wz4jRzO1jQIwwTkSoffv6oX55tWBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}