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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c175f01348f36c75f501da9690baea3cfddf9769c01fffb2f53edc679cb24d' 
  AND token = 'AIuTKjmkNdRzSoHm5Gll+ntQramfWL4OOmT6TrRo1TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}