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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f015cc573d53cfd9406c21b7421ac2d167330718f176982f5b4e0da25d8a0145' 
  AND token = 'A8fU1ORf/7LDrpvkgzr8pVZyQ57ijw/VegtFSH2XcnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}