SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bbafd776c4985b09ed2821ebe1ab877691f8f9dba4a3bf588f849c8394fc231' 
  AND token = 'h1T1z280E0VKedxTWY+T89z68qBs863edic0fSKfBEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}