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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287d2539b51cb506c181c49753dc004e3f2d2c70ed2dbe53d97907105b2f823d' 
  AND token = 'qVFVoHhmEL+DskkR4ocu1hyk+Lh+adKo4cLVskB85ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}