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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a858d4ca6fbcd2006deb00866c13d3f6401ce9695d98b0895632e5da1af6eb7' 
  AND token = 'C2yaT/prYGnTN8IT8bmgswO/EyJigJQa7g49NMfXD6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}