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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3431a1e5b17d97cd301eac9aa9fd3ef2d6987c4c4163931ef0ae184d1fe4ce49' 
  AND token = '7Sd/5t3W2i7KGykwTYKUdKYnCcg0e9xYgHY5ee2MW0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}