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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a8d9e8d5b5e0daa9c4667f0897e4e36412ba19b6553701b30baaa625399903' 
  AND token = 'BhzulxGFmV1EtKYVa69qTaNd1maDFPyj29jLzJc3fy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}