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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f75c0ca53fe564e86956d64213f321c72a76a19d3ce4957ee8cd7bbc4427253' 
  AND token = '+3APe5k2g4QyPIGWXLqsZesjbt9kSoHEcP/axUyizWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}