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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b39bf3e86e40d8262131ec4236db3b7c0289755381f36e1bf23e091097f29c94' 
  AND token = '7P7idfmcx9Thy3XKx1EGWoiJDwiNcwy6p3Fa1oO4JDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}