SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7647dc9946aeffcf167bb3cfc86e38967cf57851632ee41078945908245b4222' 
  AND token = 'CZ64yfeHuaNLj1j9eXxA6E27yOV+BY7MyOpL6xQkTck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}