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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50705a5ea101a39eb7870f51206fd0a529f091cb67dbb5943c9cb78edef56d7' 
  AND token = 'CU/XeLPDKGfURIVU7kCBoiZQEo1JgFHtyYcrdH3lUA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}