SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2ab35f0957f913a720fb7ee5d4a4ac07d40e5d74945fce436982b9c5734131' 
  AND token = 'Fu7pfI2Dkn0fJ/q1rPkwj0J1m2H8Wk1VlPn0LwKfmxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}