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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71eccb105074e833eb64907d3dbfb880b4bb28a97adc325e4d717deeb19303e8' 
  AND token = '83To3jz6FhMSwJtwxtnLgwO4i+RZS4YMdW0rMYf8WFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}