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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1048b6e46dd32d1604992ed9dee4cf379c2fd10d9fededd9c297344e898051' 
  AND token = 'MtmU7L2h+1kmbxcf52BaOD71dPt7/A2wwpZjVxLrCUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}