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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a2a4c77a7094895bff8153cb31cb88f4be26a752b495cdecc9fd9a2bb14884' 
  AND token = 'fot4jLJR7rOQOGT+sWB4OD8Lk8xrKuJG9KxJou+E+kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}