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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62e3e82c2bda278345729f91ee8c4768b8fdfb7654c56a80ffb0babab750d88c' 
  AND token = 'jb+1bb4d29n+BrNn+2Ryw1c0krTgCyOzAtLbuRapc9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}