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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf154d3413531a29b042b981c0a2831130577aa1b7eb4783cc5b656fd75e0c6' 
  AND token = 'WfJuRNYwIw+dSPQQejfI9HEgUTcttBs8YNAPZk3myQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}