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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fdf95e658af2040e363648301fd4f7dc27fc6c681ae17298a152c1087e4ce50' 
  AND token = 's78s0MEi6rmDq1pFs2A5sAybBQ8iolv3o0YL9tENGvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}