SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c6959761256b3a23f9871164ea5f7593e411268cc49cb6551c13b274c6744d' 
  AND token = '+fIN4fYUlk6AJWBJ8GlPeWaROrRpa+97UXlFJXbYG1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}