SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc277081855c5d06e215450c8fc3f6ee82880c3ad010232f61eb7027f28cf43' 
  AND token = '/IJFlAqPYhqf2M0JW2LmLd76W03r7sPfJ+NsldhlGyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}