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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b529ab209e308ef894a73ad7216c8fce429298965bf6668d0de68da45b381838' 
  AND token = 'ARVn9nvLjyCVbslDE4a/7xHVbIa2Xel95UPYPF49rHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}