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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee56dd7393b9fc901dfb993dc5d7290ddc94f39db797a7b95404f0979796495' 
  AND token = 'zC7xVhD0Du7w+UmHc6aduFxbToEtXjjJ63rzPk3lDSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}